If you aren’t lying, you are at least misrepresenting history. At the time it was 100% true. Psychoanalytic treatment was all hypothesis formulation and no hypothesis testing. CBT, IPT, and others taught therapy a lesson in how to study it. Lots work. onlinelibrary.wiley.com/doi/10.1002/cp…

The more I read, the more I get worried about psychedelic assisted psychotherapy breaking all the rules of running trials.
' Potential participants can include current and past patients of the researchers'
Current patients? For a trial you are running? Where is the equipoise?

Eiko Fried | @eikofried.bsky.social Ioana A Cristea & Florian Naudet actually got a paper's title changed (not quite enough, but changed) with a letter to the editor. Worth a read. Even as I do this work I share their concerns about our endeavors to study psychedelic drugs.
jamanetwork.com/journals/jamap…

Data Checks Before Registering Study Protocols for Health Care Database Analyses. A very interesting JAMA viewpoint:

jamanetwork.com/journals/jama/…

This ICER of MDMA-assisted psychotherapy for PTSD is an interesting (and if some of the information in it turns out to be factual; quite damning) read. icer.org/wp-content/upl…

Editors-in-Chief Joan Marsh The Lancet Psychiatry and WRief Clinical Psychology in Europe (CPE) presenting exciting current initiatives and trends in the publishing world. OpenScience, outcome measure rationalization, lived-experience involvement and more!

#UrbanMentalHealth Cornelia Weise The Centre for Urban Mental Health

If you can fit a laser pointer between the curves, you can give the #ASCO24 plenary!

The only psychedelic/hallucinogenic drug approved so far for a mental condition is esketamine. Unapproved means not only don't we know if it helps, but we don't also know about the harms.
fortune.com/well/article/p…

My feed is all insane (and insanely boring) royal ‘theories’ and the ‘great plot against meat’ ‘keto is life’ ‘glucose tracker game changer’ (wtf)!) etc fanatics and can someone please tell me when did I make a wrong click or follow and how can I redeem myself?

Twitter is so terrible that I did not even find out Frans de Waal has died until now but I am drowning in endlessly boring speculation about the British royal family.

Heterogeneity and relevance of outcomes measured in #depression trials
A thread about our new paper in The Lancet Psychiatry free access until May 2024. authors.elsevier.com/a/1ilXW7tf1d52…
Eiko Fried | @eikofried.bsky.social Toshi_FRKW Andrea Cipriani Anneka Tomlinson Viet-Thi Tran CRESS_UMR1153

Next:
'Scholarly literature mining with information retrieval and natural language processing: Tracking fake articles and decontaminating the literature'
Guillaume Cabanac ⟨here and elsewhere⟩ from Université de Toulouse will give us a tour through the gutters of bad literature!
#Inserm277

We will start day 3 of the #Inserm277 workshop in Bordeaux, with 'Role of meta-epidemiologic studies in research on research' by Ioana A Cristea Università di Padova
Main source of empirical evidence of bias in randomized trials (Conchrane Handbook).
onlinelibrary.wiley.com/doi/10.1002/jr…

First lecture yesterday by John Ioannidis at the ⁦Inserm⁩ workshop. 👌

V happy to be in Bordeaux for @INSERM #MetaResearch workshop. Prog: John Ioannidis Malcolm Macleod #FBPE Ulrich Dirnagl (@[email protected]) Carl Moons Ana Marušić Florian Naudet Marcus Munafò Daniele Fanelli Ioana A Cristea Guillaume Cabanac ⟨here and elsewhere⟩ Elisabeth Bik Philippe Ravaud Isabelle BOUTRON. Oh, & me, from PLOS Biology!

I am looking for free or easily accessible large datasets that also include some mental health data. Reason is mostly for now to field-test some design ideas.