Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profileg
Giovanni Marchegiani

@Gio_Marchegiani

Pancreas Surgeon @UniPadova 😷 @BJSOpen Editor 🗞️ @ISGPS_news Secretary 🎓 @YouppiePancreas Coordinator @EAHPBA board 🪡@MGHSurgery @PancreasVerona trained

ID:948112554882199552

linkhttp://www.linkedin.com/in/giovanni-marchegiani-930850ab/ calendar_today02-01-2018 08:43:42

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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

Continuous drain irrigation 🚒 👩‍🚒as a risk mitigation strategy for postoperative pancreatic fistula: a meta-analysis

🚿 800 pts analyzed but... limited evidence!

🐳 POPF reduction (OR 0.40)

🫵 Have you ever tried ?! 🧐

sciencedirect.com/science/articl…

Continuous drain irrigation 🚒 👩‍🚒as a risk mitigation strategy for postoperative pancreatic fistula: a meta-analysis 🚿 800 pts analyzed but... limited evidence! 🐳 POPF reduction (OR 0.40) 🫵 Have you ever tried ?! 🧐 sciencedirect.com/science/articl…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

Fluid collections 🐟 after distal pancreatectomy… real complications or just the way the pancreas heals ❤️‍🩹 ?!

💦 30 day prevalence 70% regardless of resection technique

🚨 POPF, PPAP and size > 5cm predictors of clinical relevance

🆓 link sciencedirect.com/science/articl…

Fluid collections 🐟 after distal pancreatectomy… real complications or just the way the pancreas heals ❤️‍🩹 ?! 💦 30 day prevalence 70% regardless of resection technique 🚨 POPF, PPAP and size > 5cm predictors of clinical relevance 🆓 link sciencedirect.com/science/articl…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

How to predict recurrence of a distal cholangio 🌱 after resection ?!

🏥 645 PD at 13 centers

🍒 LNR and N stage predictors of recurrence + surgical radicality

🦾 A.I. based predictive model provided (C-index 0.8) imim.shinyapps.io/LassoCholangio…

authors.elsevier.com/sd/article/S07…

How to predict recurrence of a distal cholangio 🌱 after resection ?! 🏥 645 PD at 13 centers 🍒 LNR and N stage predictors of recurrence + surgical radicality 🦾 A.I. based predictive model provided (C-index 0.8) imim.shinyapps.io/LassoCholangio… authors.elsevier.com/sd/article/S07…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

Somatostatin 🤜🤛 Octreotide for prevention of pancreatic fistula 🇫🇷 RCT for PD and DP

💉 7 days continuous IV / 4 times a day

🐳 POPF rate similar at 23% even after correction for MPD size

So… would you use ☝️,✌️, or… neither of the two?! 🤦‍♂️

journals.lww.com/annalsofsurger…

Somatostatin 🤜🤛 Octreotide for prevention of pancreatic fistula 🇫🇷 RCT for PD and DP 💉 7 days continuous IV / 4 times a day 🐳 POPF rate similar at 23% even after correction for MPD size So… would you use ☝️,✌️, or… neither of the two?! 🤦‍♂️ journals.lww.com/annalsofsurger…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

Left side pancreatectomy 🙊 do we speak the same language?!

🌍 International Delphi consensus

4️⃣ resection categories based on anatomy + additional procedures / technique 🔪🤖

👉 Distal is not just “distal”…

academic.oup.com/bjs/article-ab…

Left side pancreatectomy 🙊 do we speak the same language?! 🌍 International Delphi consensus 4️⃣ resection categories based on anatomy + additional procedures / technique 🔪🤖 👉 Distal is not just “distal”… academic.oup.com/bjs/article-ab…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

Implications of pregnancy 🤰 on mucinous neoplasms 🥑 of the pancreas

🇺🇸 🇮🇹 176 patients / 14% High grade

🫧 Size > 10 cm associated to HG

👩‍🍼 Peri gestational MCN positively correlated with cyst size

👩‍⚕️ Counseling needed on each specific case!

🆓 doi.org/10.1016/j.pan.…

Implications of pregnancy 🤰 on mucinous neoplasms 🥑 of the pancreas 🇺🇸 🇮🇹 176 patients / 14% High grade 🫧 Size > 10 cm associated to HG 👩‍🍼 Peri gestational MCN positively correlated with cyst size 👩‍⚕️ Counseling needed on each specific case! 🆓 doi.org/10.1016/j.pan.…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

🪐 The REDISCOVER Guidelines for BR and LA PDAC - part 2 🚀

💡 Unanswered questions / future perspectives include

🥀 Resection of SMA !?
🧐 Management of LA PDAC in unfit for chemo / elevated CA 19.9
💉 Numbers of chemo cycles
💥 Ablation therapies role

link.springer.com/article/10.100…

🪐 The REDISCOVER Guidelines for BR and LA PDAC - part 2 🚀 💡 Unanswered questions / future perspectives include 🥀 Resection of SMA !? 🧐 Management of LA PDAC in unfit for chemo / elevated CA 19.9 💉 Numbers of chemo cycles 💥 Ablation therapies role link.springer.com/article/10.100…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

🍇 Is there a role for adjuvant 💊 chemotherapy in resected invasive IPMN?!

🧑‍🧑‍🧒‍🧒 459 pts / 60% adjuvant chemo / 50% gemcitabine alone

🙈 No benefit for survival / recurrence

🧘‍♀️Careful! No RCT data available yet.. what is your practice ?! 🫵

academic.oup.com/bjs/article-ab…

🍇 Is there a role for adjuvant 💊 chemotherapy in resected invasive IPMN?! 🧑‍🧑‍🧒‍🧒 459 pts / 60% adjuvant chemo / 50% gemcitabine alone 🙈 No benefit for survival / recurrence 🧘‍♀️Careful! No RCT data available yet.. what is your practice ?! 🫵 academic.oup.com/bjs/article-ab…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

Surveillance of IPMN 🍇 based on competing risk analysis

👴 Age 🏥 Comorbidities 🫧 Relevant changes

🔴 75 y/old + CACI > 3 predict malignancy BUT ... death for any cause was 15% !!!

👗 Surveillance should be accordingly taylored

🆓 read 👉 gut.bmj.com/content/early/…

Surveillance of IPMN 🍇 based on competing risk analysis 👴 Age 🏥 Comorbidities 🫧 Relevant changes 🔴 75 y/old + CACI > 3 predict malignancy BUT ... death for any cause was 15% !!! 👗 Surveillance should be accordingly taylored 🆓 read 👉 gut.bmj.com/content/early/…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

The EDS my_UEG postgraduate course is always a real blast 💥 🇵🇹

👩‍🎓🧑‍🎓A massive Università di Padova delegation and even the best poster award for our Riccardo Pellegrini … I am so proud 🥹

The @EDSurgery @my_ueg postgraduate course is always a real blast 💥 🇵🇹 👩‍🎓🧑‍🎓A massive @UniPadova delegation and even the best poster award for our @Ricc_Pellegrini … I am so proud 🥹
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

Every year we perform countless MRI/MRCP for IPMNs 🍇…

☢️ Can we use a short protocol for their surveillance?! 🤷‍♂️

🥊 Interobserver agreement among radiologists says.. finally the time has come!

🆓 link to paper 👉sciencedirect.com/science/articl…

Every year we perform countless MRI/MRCP for IPMNs 🍇… ☢️ Can we use a short protocol for their surveillance?! 🤷‍♂️ 🥊 Interobserver agreement among radiologists says.. finally the time has come! 🆓 link to paper 👉sciencedirect.com/science/articl…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

🔪 A whipple is not a whipple without Henle’s trunk 🪵 identification…

👉Do you know all its variants ?! 👈

🎯 Check them all out here !!! … and have a great (and safe) next whipple you all!!!

🔪 A whipple is not a whipple without Henle’s trunk 🪵 identification… 👉Do you know all its variants ?! 👈 🎯 Check them all out here !!! … and have a great (and safe) next whipple you all!!!
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

God save the ... spleen! 🫘

Distal Pancreatectomy for body PDAC: is Splenectomy necessary? 🧐

🇫🇷 PSM analysis spleen preserving had ⬇️ harvested LN but ...

🐳 Less POPF and CCI
🪽 Same risk recurrence / survival

link.springer.com/article/10.124…

God save the ... spleen! 🫘 Distal Pancreatectomy for body PDAC: is Splenectomy necessary? 🧐 🇫🇷 PSM analysis spleen preserving had ⬇️ harvested LN but ... 🐳 Less POPF and CCI 🪽 Same risk recurrence / survival link.springer.com/article/10.124…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

I have never seen so many YOUNG HPB surgeons as at AICEP E-AHPBA 🇮🇹 😳!!!

The future of our surgery looks finally bright, indeed! 💫

Thank you for these special days, and congrats to Gaetano Corvino for winning the Robot 🤖 contest (@HoggNDMD you should be proud 🥹…)

I have never seen so many YOUNG HPB surgeons as at @Aicep4 @EAHPBA 🇮🇹 😳!!! The future of our surgery looks finally bright, indeed! 💫 Thank you for these special days, and congrats to @GaetanoCorvino2 for winning the Robot 🤖 contest (@HoggNDMD you should be proud 🥹…)
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

A neglected though fundamental topic in pancreas cancer and surgical oncology: 👉 palliative surgery 👈

👘 Palliative derives from Latin “pallium” meaning “cape” aimed at protecting

🙏 Alleviate symptoms in patient with serious, life-limiting illness

academic.oup.com/bjs/article-ab…

A neglected though fundamental topic in pancreas cancer and surgical oncology: 👉 palliative surgery 👈 👘 Palliative derives from Latin “pallium” meaning “cape” aimed at protecting 🙏 Alleviate symptoms in patient with serious, life-limiting illness academic.oup.com/bjs/article-ab…
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

💥 Pancreas2000 Course 🔟 that’s a wrap 💥

At the stunning ChampalimaudF 🇵🇹 for an inspiring last meeting with top notch faculty and mentees.

The future of pancreatology is in good hands! 🙌

… see you at EPC-Europ Pancr Club in Santiago 🇪🇸!!!

💥 Pancreas2000 Course 🔟 that’s a wrap 💥 At the stunning @ChampalimaudF 🇵🇹 for an inspiring last meeting with top notch faculty and mentees. The future of pancreatology is in good hands! 🙌 … see you at @EurPancClub in Santiago 🇪🇸!!!
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

Celebrating 🎉 the brand new Swiss chapter of E-AHPBA 🇨🇭in Lausanne

Merci beaucoup Emmanuel Melloul for the warm hospitality in the city of Olympic Games at Visceral CHUV 🏔️

Celebrating 🎉 the brand new Swiss chapter of @EAHPBA 🇨🇭in Lausanne Merci beaucoup @EmmanuelMelloul for the warm hospitality in the city of Olympic Games at @VisceralChuv 🏔️
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

So, this has been published by Elsevier as many already know… 🤷‍♂️

Nothing against the use of ChatAI per se but… what about the peer review process?!

🤔 Can the current system remain the same?! Thoughts 💭?!

So, this has been published by @ElsevierConnect as many already know… 🤷‍♂️ Nothing against the use of @_ChatAI_ per se but… what about the peer review process?! 🤔 Can the current system remain the same?! Thoughts 💭?!
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Giovanni Marchegiani(@Gio_Marchegiani) 's Twitter Profile Photo

Do you drain 💦 a distal pancreatectomy?! 🧐

🚨 Practice changing RCT The Lancet Gastroenterology & Hepatology 🇳🇱 🇮🇹 282 pts

✋ NO drain better outcomes!

⬇️ Major Morbidity 15% vs. 20%
⬇️ POPF 12% vs. 27%

👉Drainless DP new standard! 👈

🆓 download 👉sciencedirect.com/science/articl…

Do you drain 💦 a distal pancreatectomy?! 🧐 🚨 Practice changing RCT @LancetGastroHep 🇳🇱 🇮🇹 282 pts ✋ NO drain better outcomes! ⬇️ Major Morbidity 15% vs. 20% ⬇️ POPF 12% vs. 27% 👉Drainless DP new standard! 👈 🆓 download 👉sciencedirect.com/science/articl…
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