Be sure to register for this year's conference! With keynotes from Doran Lab HarrisTryon Lab Marvin Whiteley and Wolfgang Lab

wriver.sites.unlv.edu

Happy to highlight our newly posted paper
biorxiv.org/content/10.110…
We show that P. aeruginosa prophages encode a component of the type IV pilus. This protein, which is homologous to the bacterial FimU protein, can be incorporated into the type IV pilus.

Join me this summer at the Beaver Run Resort in Breckenridge, Colorado for the Wind River Meeting on Prokaryotic Biology (Wind River Prokaryotic Conference )! This 5-day, trainee-focused meeting is so enlightening & fun! I hope to see you there :)

More info & register here: wriver.sites.unlv.edu

I am recruiting a bioinformatics postdoc for developing bioinformatic pipelines for viral discovery and viromics to start in the Fall 2024.

Please check out the job posting here: integrativeviromicslab.com/open-positions

x.com/gregory_annc/s…

#Salmonella Stress Mantra: 'When life gives phages, make fragments...of tRNA.' Our latest work in Science Magazine unveils how a 'Prophage terminase with tRNase activity sensitizes Salmonella enterica to oxidative stress' | Science science.org/doi/10.1126/sc…

Excited to share that our Science paper is online now! Small viruses of bacteria can be used to disarm pathogenic bacteria, for example, phage PP7 to disarm human pathogen Pseudomonas aeruginosa in this paper.

science.org/doi/10.1126/sc…

Just missing April fool's, here is something that is no laughing matter:
nature.com/articles/s4156…
In Nature Microbiology, we describe how a prophage avoids autoimmunity from its own defence systems

The abstract submissions for #VoM2024 reveal a strong interest in Phage Therapy and Virus-Host Interaction📝

Get ready for insightful sessions featuring invited speakers who will delve deep into these cutting-edge topics:
vom2024.org/speakers

Insertion sequence-driven evolution of microbiota. Duerkop Lab Andrew Hryckowian & Kirsch develop pipeline that reveals presence, abundance & dynamics of IS insertions in human intestinal #microbiota and their roles in genome diversification & adaptation cell.com/cell-host-micr…

In a new study lead by Josh Kirsch and in collaboration with Andrew Hryckowian, we provide a comprehensive IS database for use with polymicrobial MAGs. We show that IS insertions target accessory genes within the microbiota that support gut adaptation. cell.com/cell-host-micr…

Did you know that some phages can switch genetic codes during infection via the use of suppressor tRNAs?
We identified a ribozyme group which appears to be crucial for this process!
Read the original article: rdcu.be/dANOT
Or the press release: tinyurl.com/thetarz

The defensome of complex bacterial communities | Nature Communications nature.com/articles/s4146…

OUT NOW! Diverse plasmid systems and their ecology across human gut metagenomes revealed by PlasX and MobMess

Michael Yu Emily Fogarty A. Murat Eren (Meren)

nature.com/articles/s4156…

I am very happy to report that the years of work we put into studying the ecology and evolution of a single cryptic human gut plasmid is now nicely summarized in a paper that just appeared in Cell:

sciencedirect.com/science/articl…

Here is a 🧵 to cover some take home messages.

The deadline has been extended to April 30th. Please send in your enterococcal papers. We’d love to review them!!

Really glad to see this out - we now know a lot about the diversity and distribution of enterococci on Earth. Good work Julia, Francois, Ashlee and the rest of the team! doi.org/10.1073/pnas.2…

Not good

Our latest on phage-plasmids(PP) is out! See Eugen Pfeifer thread. 2 main findings. PP recombine more with (other) plasmids and phages than the latter, thereby connecting them. PP can become just phages or plasmids, which may transition to be conjugative. All the world’s an MGE!

Emma Sheriff and Shelby E. Andersen from Duerkop Lab recently published a genome announcement for a new phage isolated from water from the Ganges River! Read the entire manuscript here:
pubmed.ncbi.nlm.nih.gov/38294211/

ASM #MRAJournal

Tiny viruses called phages offer a way to fight bacterial infections when antibiotics stop working, but researchers are finding that they're not miracle treatments. My latest for WIRED: wired.com/story/phage-th…