Our Statement AHA Science Circulation
Patient-Centered Adult CV Care
🏥Patient-centered care: main tenet of contemporary healthcare
🤝Can improve health equity & outcomes
🫀CV professionals should incorporate patient-centered care strategies routinely
📎shorturl.at/wRUY6

Courtesy of The Frustrated Researchers facebook.com/TheFrustratedR…

Cool meta-analysis on long-term benefits of sodium substitution! Huge need for more trials in a more diverse range of cultural settings like the US. acpjournals.org/doi/10.7326/M2…

Thanks Mingyu Zhang, PhD, MHS for sharing the article with me!

Check out the recording of the excellent discussion around estimating GFR from Pierre Delanaye

CKD-EPI, EKFC, Iohexol clearance or Cystatin C?

youtu.be/2gScckBmFDw

#NephGR

(1/2) In the aftermath of #ACC24 , it is a good time to review one of the best articles ever written on interpreting clinical trials by Dr. Robert M. Califf :
shorturl.at/qtAK2

Robert Harrington C. Michael Gibson MD Rasha Al-Lamee

Excited to present this work at #ACC24 and have #SimPub JACC Journals #JACCHF .

So grateful for the incredible support and mentorship from Steve Greene and the team Muthu Vaduganathan Gregg Fonarow MD!!

Duke Cardiology Fellows Duke Clinical Research Institute Robert Mentz, MD Marat Fudim, MD MHS

#CircACC24 #SimPub SGLT2i Trialists Consortium: primary benefit of SGLT2i for MACE driven by reduction in CV death, without clear effect on myocardial infarction or stroke Sid M. Patel TIMI Study Group #AHAJournals ahajournals.org/doi/10.1161/CI…

Took side tour to Georgia Aquarium near hotel. It is mesmerizing. I can watch all day long !

#LBCT KARDIA2 in #ACC24 : one single dosis zilebesiran 600mg. Add-on antihypertensive treatment in patient with uncontrolled hypertension was associated with increased risk of adverse effects. The results support the potencial biannual dosis of zib 600.

Kardia 1 trial in #ACC24 : efficacy and safety of zilebesiran in patient with hypertension. Key point: plasma renin concentration(PRC) and race. Everything indicates that renin concentrations will be key for the upcoming studies on hypertension: Bax-HTN, Target-HTN and Kardia 3

Routine Beta-Blockers in Secondary Prevention — On Injured Reserve | New England Journal of Medicine nejm.org/doi/full/10.10…

Interesting results from KARDIA2 that show relatively modest reduction in 24ABP when added on top of olmesartan relative to indapamide or amlodipine. This seems to be similar to less effective BP lowering of duo ACEI-ARB or DRI-ARB.

Join us for the latest in resistant HTN in B313A with Jennifer Cluett, MD Steven Smith @8AM ! #ACC24

Congrats to the NCAR award winners! Particularly my friends/colleagues Chris Hearon Jr. & Claire Kissell (née Trotter) 😀

Claire's poster is this evening [Saturday, P360] if you missed her talk, and Denis Wakeham is presenting some of the work with Chris at his poster [P344] today too!

Please join us this evening for this outstanding clinical spotlight session with hypertension experts. Learn about new therapies to treat resistant hypertension. American College of Cardiology #ACC24

AEGIS-II trial shows in AMI pts with multivessel disease + additional CV risk factors and on GDMT, 4 weekly infusions of CSL112 did not reduce primary endpoint of CV death, MI, or stroke thru 90 days. Additional analysis shows CV outcome benefits statistically significant in pts…

Check out this recent publication from John Giacona, PhD, PA-C🫀, PhD, PA-C, CHC, 'HDL-C and Apolipoprotein A-I are Independently Associated with Skeletal Muscle Mitochondrial Function in Healthy Humans' at bit.ly/48QJnND 📰

Our Department Chair Curt D. Sigmund, PhD received the APS Presidential Outstanding Service Award from American Physiological Society,

Interesting long-term follow-up data from ASCOT.

Legacy benefits of blood pressure treatment on cardiovascular events are primarily mediated by improved blood pressure variability: the ASCOT trial academic.oup.com/eurheartj/arti…

RCT

Empagliflozin effective in ⬇️ liver fat in people with and without T2 diabetes.

⬇️ in liver fat content is independent of the ⬇️ in plasma glucose

Strongly associated with ⬇️ in body weight & improvement in insulin sensitivity

diabetesjournals.org/care/article-a…