Remarkable team effort with 100s of collaborators: cross-disorder genetics across 8 psych disorders (N = 727K) PGC Consortium Analyses led by Phil Lee, w/ Verneri Anttila Hyejung Won Anne Feng @Andrew_Grotz Elliot Tucker-Drob @michelnivard Ken Kendler + many more authors.elsevier.com/a/1aDRcL7PXYX9β¦
So many common genomic threads across 8 neuropsychiatric conditions from this analysis of > 725,000 people cell.com/cell/fulltext/β¦ by Jordan Smoller PGC Consortium Verneri Anttila Hyejung Won Anne Feng @Andrew_Grotz Elliot Tucker-Drob @michelnivard + a big collaborative network Cell Press
Multivariate Modeling of Direct and Proxy GWAS Indicates Substantial Common Variant Heritability of Alzheimer's Disease | @delaFuente_UT @Andrew_Grotz @michelnivard MarioniGroup | medrxiv.org/content/10.110β¦
Check out this exciting study by Andrew Grotzinger (@Andrew_Grotz) and colleagues in Nature Genetics, where they examined shared genetic architecture across 11 major psychiatric disorders! nature.com/articles/s4158β¦
Multivariate genomic architecture of cortical thickness and surface area at multiple levels of analysis
Kudos to @Andrew_Grotz Travis Mallard Zhaowen Liu Tian Ge Jakob Seidlitz
rdcu.be/c6hpy
New preprint! Comparison of the Multivariate Genetic Architecture of Eight Major Psychiatric Disorders Across Sex
medrxiv.org/content/10.110β¦
w Elliot Tucker-Drob, Travis Mallard, Adam Maihofer, Mijke Rhemtulla, Phil Lee, Jordan Smoller, @michelnivard, & @Andrew_Grotz π§΅:
I have openings for postdocs to work with @michelnivard, @Andrew_Grotz, and me on Genomic SEM, psychiatric genetics, and related topics in statistical genetics. Email [email protected] for details.
Scholarships Oxford Genomics 4 Social Science Summer School June 15-19 for attendance or travel & accommodation - based on need & #Diversity Apply by 15 March! Dalton Conley Molly Przeworski Nicola Barban Felix C. Tropf @Andrew_Grotz
oxford-genomics-summerschool.com
Ever look at βatlasesβ of genetic correlations and wonder else what you could do with them? Check out Genomic SEM, led by Elliot Tucker-Drob @michelnivard and the indefatigable @Andrew_Grotz. twitter.com/tuckerdrob/staβ¦
The PGC Worldwide Lab talk by Elliot Tucker-Drob is now up on youtube youtu.be/ECwQS5UD3YM - awesome work and congrats too to @michelnivard and @Andrew_Grotz on developing this awesome method to advance GWAS analysis.
SNP-based heritability may be higher than we thought from @Andrew_Grotz Elliot Tucker-Drob @michelnivard et al
Pervasive Downward Bias in Estimates of Liability-Scale Heritability in Genome-wide Association Study Meta-analysis: A Simple Solution biologicalpsychiatryjournal.com/article/S0006-β¦
New results from the Texas Twin Project: intelligence and emotional control in relation to a network of psychopathology sx in adolescence (w/ JMadole @Andrew_Grotz Mijke Rhemtulla Elliot Tucker-Drob) journals.sagepub.com/doi/10.1177/21β¦
**New work led by @Andrew_Grotz using transcriptome-wide SEM to identify 466 genes associated with transdiagnostic risk across 13 psychiatric disorders and multiple targets for drug repurposing
With Kritika Singh Max Lam Travis Mallard Tian Ge et al.
jamanetwork.com/journals/jamapβ¦
Today at the SGDP Centre KCL, Elliot Tucker-Drob and @Andrew_Grotz are telling us all about GenomicSEM! A thread... (because @michelnivard demanded one)
𧬠Using a sample of >1M people AlexanderSHatoum et al find genomic loci associated with #addiction risk π
Sarah Colbert Emma Johnson Gita ππ𧬠Sarah Paul Nicole Karcher David Baranger @Andrew_Grotz Elliot Tucker-Drob Renato Polimanti H Edenberg
nature.com/articles/s4422β¦
β¨ ONLINE TODAY Nature Genetics
π° Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis π§
π©πΎβπ€βπ¨πΌ @Andrew_Grotz and colleagues
ππΎπ§¬ππΎ
go.nature.com/3sC4bX9